ARBICLO 

​What does the medicine do?

Injectable artesunate is the WHO recommended treatment for severe Plasmodium falciparum malaria in children and adults. This short-acting drug kills parasites more quickly than conventional antimalarials, in particular because it is active on the asexual and sexual multiplication of the parasite. By attacking all stages of the parasite's life cycle, from that of the ring trophozoite, this medication allows for faster healing. The elimination of artesunate is very rapid, and its antimalarial activity is determined by the elimination of dihydroartemisinin (half-life equal to approximately 45 minutes).

​Dose:

® For children < 20 kg: 3.0 mg/kg

® For children & adults > 20 kg: 2.4 mg/kg

Can be given intravenously or intramuscularly

The intravenous route is preferable to the intramuscular route.